BDBM50392116 CHEMBL2152618

SMILES: NC(=O)c1ccccc1Nc1cccc(OCCc2ccccc2C(F)(F)F)c1

InChI Key: InChIKey=RSRZESOZAMAJGF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50392116   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-Dependent Deacetylase Sirtuin-1 (Homo sapiens (Human))	BDBM50392116 (CHEMBL2152618) Show SMILES NC(=O)c1ccccc1Nc1cccc(OCCc2ccccc2C(F)(F)F)c1 Show InChI InChI=1S/C22H19F3N2O2/c23-22(24,25)19-10-3-1-6-15(19)12-13-29-17-8-5-7-16(14-17)27-20-11-4-2-9-18(20)21(26)28/h1-11,14,27H,12-13H2,(H2,26,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT1 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b...				J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS
					More data for this Ligand-Target Pair
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human))	BDBM50392116 (CHEMBL2152618) Show SMILES NC(=O)c1ccccc1Nc1cccc(OCCc2ccccc2C(F)(F)F)c1 Show InChI InChI=1S/C22H19F3N2O2/c23-22(24,25)19-10-3-1-6-15(19)12-13-29-17-8-5-7-16(14-17)27-20-11-4-2-9-18(20)21(26)28/h1-11,14,27H,12-13H2,(H2,26,28)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT2 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b...				J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS
					More data for this Ligand-Target Pair