BDBM50392230 CHEMBL2153186

SMILES: CCCSc1nc(Oc2cccc(CCC(O)=O)c2)ccc1C(=O)NC1CCCCC1

InChI Key: InChIKey=PZOGIDOAFWRMRR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50392230   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50392230 (CHEMBL2153186) Show SMILES CCCSc1nc(Oc2cccc(CCC(O)=O)c2)ccc1C(=O)NC1CCCCC1 Show InChI InChI=1S/C24H30N2O4S/c1-2-15-31-24-20(23(29)25-18-8-4-3-5-9-18)12-13-21(26-24)30-19-10-6-7-17(16-19)11-14-22(27)28/h6-7,10,12-13,16,18H,2-5,8-9,11,14-15H2,1H3,(H,25,29)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged full length human 11betaHSD1 expressed in baculovirus infected cells using cortisone as substrate after 25 mins ...				J Med Chem 55: 5951-64 (2012) Article DOI: 10.1021/jm300592r BindingDB Entry DOI: 10.7270/Q24F1RTK
					More data for this Ligand-Target Pair