BDBM50392350 CHEMBL2151479

SMILES: Cc1cccc(c1)S(=O)(=O)N1CC(C1)c1nc(no1)-c1cccc(Cl)c1

InChI Key: InChIKey=FMFOJRFCJXRDIA-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50392350   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50392350 (CHEMBL2151479) Show SMILES Cc1cccc(c1)S(=O)(=O)N1CC(C1)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C18H16ClN3O3S/c1-12-4-2-7-16(8-12)26(23,24)22-10-14(11-22)18-20-17(21-25-18)13-5-3-6-15(19)9-13/h2-9,14H,10-11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA Curated by ChEMBL					Assay Description Negative allosteric modulation of human mGluR5 expressed in recombinant HEK293 cells by FLIPR assay				Bioorg Med Chem Lett 22: 6469-74 (2012) Article DOI: 10.1016/j.bmcl.2012.08.044 BindingDB Entry DOI: 10.7270/Q23F4QR3
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50392350 (CHEMBL2151479) Show SMILES Cc1cccc(c1)S(=O)(=O)N1CC(C1)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C18H16ClN3O3S/c1-12-4-2-7-16(8-12)26(23,24)22-10-14(11-22)18-20-17(21-25-18)13-5-3-6-15(19)9-13/h2-9,14H,10-11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR5 expressed in recombinant HEK293 cells by FLIPR assay				Bioorg Med Chem Lett 22: 6469-74 (2012) Article DOI: 10.1016/j.bmcl.2012.08.044 BindingDB Entry DOI: 10.7270/Q23F4QR3
					More data for this Ligand-Target Pair