BDBM50392595 CHEMBL2153392

SMILES: CC\N=C\C(=O)N=S(C)(=O)c1ccc(cc1)C(=O)Nc1c(OC)cc(Cl)cc1C(=O)Nc1ccc(Cl)cn1

InChI Key: InChIKey=IOZJDHIXYAXEDW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50392595   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50392595 (CHEMBL2153392) Show SMILES CC\N=C\C(=O)N=S(C)(=O)c1ccc(cc1)C(=O)Nc1c(OC)cc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C25H25Cl2N5O5S/c1-4-28-14-22(33)32-38(3,36)18-8-5-15(6-9-18)24(34)31-23-19(11-17(27)12-20(23)37-2)25(35)30-21-10-7-16(26)13-29-21/h5-14,38H,4H2,1-3H3,(H,31,34)(H,29,30,35)(H,32,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Inhibition of human F10a using S-2765 as substrate after 45 mins				Eur J Med Chem 58: 136-52 (2012) Article DOI: 10.1016/j.ejmech.2012.10.005 BindingDB Entry DOI: 10.7270/Q2571D4Q
					More data for this Ligand-Target Pair