BDBM50392662 CHEMBL2153823

SMILES: CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(OC)cc23)c1C

InChI Key: InChIKey=BZJOMWRFPIGJEH-AQTBWJFISA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50392662   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50392662 (CHEMBL2153823) Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(OC)cc23)c1C Show InChI InChI=1S/C23H30N4O3/c1-6-27(7-2)11-10-24-23(29)21-14(3)20(25-15(21)4)13-18-17-12-16(30-5)8-9-19(17)26-22(18)28/h8-9,12-13,25H,6-7,10-11H2,1-5H3,(H,24,29)(H,26,28)/b18-13-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a
Universidad de Talca Curated by ChEMBL					Assay Description Binding affinity to DNA-tagged VEGFR2 by qPCR based competitive binding assay				Eur J Med Chem 58: 272-80 (2012) Article DOI: 10.1016/j.ejmech.2012.10.020 BindingDB Entry DOI: 10.7270/Q2N58NGD
					More data for this Ligand-Target Pair