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SMILES: OC1(CC(=O)c2ccc(cc2)-c2cccc(Cl)c2)C(=O)NC(=O)NC1=O

InChI Key: InChIKey=HWKBTEUWFWNXHM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50392684   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50392684 (CHEMBL2151353) Show SMILES OC1(CC(=O)c2ccc(cc2)-c2cccc(Cl)c2)C(=O)NC(=O)NC1=O Show InChI InChI=1S/C18H13ClN2O5/c19-13-3-1-2-12(8-13)10-4-6-11(7-5-10)14(22)9-18(26)15(23)20-17(25)21-16(18)24/h1-8,26H,9H2,(H2,20,21,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari Aldo Moro Curated by ChEMBL					Assay Description Inhibition of MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg as substrate incubated for 30 mins prior to substrate addition measured after 3 hrs by fluor...				Eur J Med Chem 58: 368-76 (2012) Article DOI: 10.1016/j.ejmech.2012.09.036 BindingDB Entry DOI: 10.7270/Q28053QN
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50392684 (CHEMBL2151353) Show SMILES OC1(CC(=O)c2ccc(cc2)-c2cccc(Cl)c2)C(=O)NC(=O)NC1=O Show InChI InChI=1S/C18H13ClN2O5/c19-13-3-1-2-12(8-13)10-4-6-11(7-5-10)14(22)9-18(26)15(23)20-17(25)21-16(18)24/h1-8,26H,9H2,(H2,20,21,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari Aldo Moro Curated by ChEMBL					Assay Description Inhibition of recombinant MMP8 catalytic site using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg as substrate incubated for 30 mins prior to substrate addition me...				Eur J Med Chem 58: 368-76 (2012) Article DOI: 10.1016/j.ejmech.2012.09.036 BindingDB Entry DOI: 10.7270/Q28053QN
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50392684 (CHEMBL2151353) Show SMILES OC1(CC(=O)c2ccc(cc2)-c2cccc(Cl)c2)C(=O)NC(=O)NC1=O Show InChI InChI=1S/C18H13ClN2O5/c19-13-3-1-2-12(8-13)10-4-6-11(7-5-10)14(22)9-18(26)15(23)20-17(25)21-16(18)24/h1-8,26H,9H2,(H2,20,21,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.98E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari Aldo Moro Curated by ChEMBL					Assay Description Inhibition of recombinant MMP9 catalytic site using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg as substrate incubated for 30 mins prior to substrate addition me...				Eur J Med Chem 58: 368-76 (2012) Article DOI: 10.1016/j.ejmech.2012.09.036 BindingDB Entry DOI: 10.7270/Q28053QN
					More data for this Ligand-Target Pair