BDBM50392689 CHEMBL2151358

SMILES: COc1ccc(cc1)-c1ccc(cc1)C(=O)CC1(O)C(=O)NC(=O)NC1=O

InChI Key: InChIKey=AGAWLHFJRLMKEA-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50392689   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50392689 (CHEMBL2151358) Show SMILES COc1ccc(cc1)-c1ccc(cc1)C(=O)CC1(O)C(=O)NC(=O)NC1=O Show InChI InChI=1S/C19H16N2O6/c1-27-14-8-6-12(7-9-14)11-2-4-13(5-3-11)15(22)10-19(26)16(23)20-18(25)21-17(19)24/h2-9,26H,10H2,1H3,(H2,20,21,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	121	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari Aldo Moro Curated by ChEMBL					Assay Description Inhibition of MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg as substrate incubated for 30 mins prior to substrate addition measured after 3 hrs by fluor...				Eur J Med Chem 58: 368-76 (2012) Article DOI: 10.1016/j.ejmech.2012.09.036 BindingDB Entry DOI: 10.7270/Q28053QN
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50392689 (CHEMBL2151358) Show SMILES COc1ccc(cc1)-c1ccc(cc1)C(=O)CC1(O)C(=O)NC(=O)NC1=O Show InChI InChI=1S/C19H16N2O6/c1-27-14-8-6-12(7-9-14)11-2-4-13(5-3-11)15(22)10-19(26)16(23)20-18(25)21-17(19)24/h2-9,26H,10H2,1H3,(H2,20,21,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	184	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari Aldo Moro Curated by ChEMBL					Assay Description Inhibition of recombinant MMP8 catalytic site using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg as substrate incubated for 30 mins prior to substrate addition me...				Eur J Med Chem 58: 368-76 (2012) Article DOI: 10.1016/j.ejmech.2012.09.036 BindingDB Entry DOI: 10.7270/Q28053QN
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50392689 (CHEMBL2151358) Show SMILES COc1ccc(cc1)-c1ccc(cc1)C(=O)CC1(O)C(=O)NC(=O)NC1=O Show InChI InChI=1S/C19H16N2O6/c1-27-14-8-6-12(7-9-14)11-2-4-13(5-3-11)15(22)10-19(26)16(23)20-18(25)21-17(19)24/h2-9,26H,10H2,1H3,(H2,20,21,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	141	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari Aldo Moro Curated by ChEMBL					Assay Description Inhibition of recombinant MMP9 catalytic site using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg as substrate incubated for 30 mins prior to substrate addition me...				Eur J Med Chem 58: 368-76 (2012) Article DOI: 10.1016/j.ejmech.2012.09.036 BindingDB Entry DOI: 10.7270/Q28053QN
					More data for this Ligand-Target Pair