BDBM50392694 CHEMBL2151363

SMILES: NC(=O)c1ccc(cc1)-c1ccc(cc1)C(=O)CC1(O)C(=O)NC(=O)NC1=O

InChI Key: InChIKey=OROXFGPUFVFZQS-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50392694   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50392694 (CHEMBL2151363) Show SMILES NC(=O)c1ccc(cc1)-c1ccc(cc1)C(=O)CC1(O)C(=O)NC(=O)NC1=O Show InChI InChI=1S/C19H15N3O6/c20-15(24)13-7-3-11(4-8-13)10-1-5-12(6-2-10)14(23)9-19(28)16(25)21-18(27)22-17(19)26/h1-8,28H,9H2,(H2,20,24)(H2,21,22,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari Aldo Moro Curated by ChEMBL					Assay Description Inhibition of MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg as substrate incubated for 30 mins prior to substrate addition measured after 3 hrs by fluor...				Eur J Med Chem 58: 368-76 (2012) Article DOI: 10.1016/j.ejmech.2012.09.036 BindingDB Entry DOI: 10.7270/Q28053QN
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50392694 (CHEMBL2151363) Show SMILES NC(=O)c1ccc(cc1)-c1ccc(cc1)C(=O)CC1(O)C(=O)NC(=O)NC1=O Show InChI InChI=1S/C19H15N3O6/c20-15(24)13-7-3-11(4-8-13)10-1-5-12(6-2-10)14(23)9-19(28)16(25)21-18(27)22-17(19)26/h1-8,28H,9H2,(H2,20,24)(H2,21,22,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	586	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari Aldo Moro Curated by ChEMBL					Assay Description Inhibition of recombinant MMP8 catalytic site using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg as substrate incubated for 30 mins prior to substrate addition me...				Eur J Med Chem 58: 368-76 (2012) Article DOI: 10.1016/j.ejmech.2012.09.036 BindingDB Entry DOI: 10.7270/Q28053QN
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50392694 (CHEMBL2151363) Show SMILES NC(=O)c1ccc(cc1)-c1ccc(cc1)C(=O)CC1(O)C(=O)NC(=O)NC1=O Show InChI InChI=1S/C19H15N3O6/c20-15(24)13-7-3-11(4-8-13)10-1-5-12(6-2-10)14(23)9-19(28)16(25)21-18(27)22-17(19)26/h1-8,28H,9H2,(H2,20,24)(H2,21,22,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari Aldo Moro Curated by ChEMBL					Assay Description Inhibition of recombinant MMP9 catalytic site using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg as substrate incubated for 30 mins prior to substrate addition me...				Eur J Med Chem 58: 368-76 (2012) Article DOI: 10.1016/j.ejmech.2012.09.036 BindingDB Entry DOI: 10.7270/Q28053QN
					More data for this Ligand-Target Pair