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SMILES: Fc1ccc(cc1Cl)-c1ccc(cc1)-c1nnc(CCCc2ccc3cccnc3n2)o1

InChI Key: InChIKey=FNQGVMZOLBAJFA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50393149   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Succinate receptor 1


(Homo sapiens (Human))		BDBM50393149
PNG
(CHEMBL2153587)
Show SMILES Fc1ccc(cc1Cl)-c1ccc(cc1)-c1nnc(CCCc2ccc3cccnc3n2)o1
Show InChI InChI=1S/C25H18ClFN4O/c26-21-15-19(11-13-22(21)27)16-6-8-18(9-7-16)25-31-30-23(32-25)5-1-4-20-12-10-17-3-2-14-28-24(17)29-20/h2-3,6-15H,1,4-5H2
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Advinus Therapeutics

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...

Bioorg Med Chem Lett 21: 3596-602 (2011)


Article DOI: 10.1016/j.bmcl.2011.04.091
BindingDB Entry DOI: 10.7270/Q2BK1DG6
More data for this
Ligand-Target Pair