BDBM50393641 CHEMBL2158686
SMILES: CCCCCCCCc1ccc(CC[C@@](N)(CO)COC)cc1
InChI Key: InChIKey=YEYZALQTJCVXIJ-HXUWFJFHSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50393641 (CHEMBL2158686) | UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The City University of New York Curated by ChEMBL | Assay Description Inhibition of SK2 (unknown origin) | Medchemcomm 4: (2013) Article DOI: 10.1039/c3md00201b BindingDB Entry DOI: 10.7270/Q2736TWP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase types 2 (SphK2) (Homo sapiens (Human)) | BDBM50393641 (CHEMBL2158686) | UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Tech Curated by ChEMBL | Assay Description Inhibition of SphK2 (unknown origin) | ACS Med Chem Lett 7: 229-34 (2016) BindingDB Entry DOI: 10.7270/Q22B90ZN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50393641 (CHEMBL2158686) | UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | 1.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase types 2 (SphK2) (Homo sapiens (Human)) | BDBM50393641 (CHEMBL2158686) | UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Tech Curated by ChEMBL | Assay Description Inhibition of SphK2 using sphingosine as substrate and [32gammaP]ATP after 15 to 20 mins by Cerenkov counting analysis | Bioorg Med Chem Lett 22: 6817-20 (2012) Article DOI: 10.1016/j.bmcl.2012.01.050 BindingDB Entry DOI: 10.7270/Q22Z16MT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase types 2 (SphK2) (Homo sapiens (Human)) | BDBM50393641 (CHEMBL2158686) | UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
500 University Drive Curated by ChEMBL | Assay Description Inhibition of SphK2 (unknown origin) | J Med Chem 57: 5509-24 (2014) Article DOI: 10.1021/jm4011687 BindingDB Entry DOI: 10.7270/Q2474CF5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase types 2 (SphK2) (Homo sapiens (Human)) | BDBM50393641 (CHEMBL2158686) | UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan. Electronic address: hohno@pharm.kyoto-u.ac.jp. Curated by ChEMBL | Assay Description Inhibition of human SphK2 using sphingosine as substrate after 15 to 20 mins in presence of [gamma-32P]ATP by Cerenkov counting method | Bioorg Med Chem 25: 3046-3052 (2017) Article DOI: 10.1016/j.bmc.2017.03.059 BindingDB Entry DOI: 10.7270/Q2XD144Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 1 (SPHK1) (Homo sapiens (Human)) | BDBM50393641 (CHEMBL2158686) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan. Electronic address: hohno@pharm.kyoto-u.ac.jp. Curated by ChEMBL | Assay Description Inhibition of human SphK1 using sphingosine as substrate after 15 to 20 mins in presence of [gamma-32P]ATP by Cerenkov counting method | Bioorg Med Chem 25: 3046-3052 (2017) Article DOI: 10.1016/j.bmc.2017.03.059 BindingDB Entry DOI: 10.7270/Q2XD144Z | |||||||||||
More data for this Ligand-Target Pair |