null

SMILES: O=c1cc(nc(NCc2cccc3ccccc23)[nH]1)N1CCOCC1

InChI Key: InChIKey=VNMOCXVCBXMWMT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50393984   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50393984 (CHEMBL2158436) Show SMILES O=c1cc(nc(NCc2cccc3ccccc23)[nH]1)N1CCOCC1 Show InChI InChI=1S/C19H20N4O2/c24-18-12-17(23-8-10-25-11-9-23)21-19(22-18)20-13-15-6-3-5-14-4-1-2-7-16(14)15/h1-7,12H,8-11,13H2,(H2,20,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PI3K p110gamma				Bioorg Med Chem Lett 22: 6665-70 (2012) Article DOI: 10.1016/j.bmcl.2012.08.101 BindingDB Entry DOI: 10.7270/Q27H1KPB
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50393984 (CHEMBL2158436) Show SMILES O=c1cc(nc(NCc2cccc3ccccc23)[nH]1)N1CCOCC1 Show InChI InChI=1S/C19H20N4O2/c24-18-12-17(23-8-10-25-11-9-23)21-19(22-18)20-13-15-6-3-5-14-4-1-2-7-16(14)15/h1-7,12H,8-11,13H2,(H2,20,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant His6-tagged PI3K p110beta expressed in baculovirus using DiC8-PI(4,5)P2 as substrate after 20 mins by AlphaScreen ass...				Bioorg Med Chem Lett 22: 6665-70 (2012) Article DOI: 10.1016/j.bmcl.2012.08.101 BindingDB Entry DOI: 10.7270/Q27H1KPB
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50393984 (CHEMBL2158436) Show SMILES O=c1cc(nc(NCc2cccc3ccccc23)[nH]1)N1CCOCC1 Show InChI InChI=1S/C19H20N4O2/c24-18-12-17(23-8-10-25-11-9-23)21-19(22-18)20-13-15-6-3-5-14-4-1-2-7-16(14)15/h1-7,12H,8-11,13H2,(H2,20,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant His6-tagged PI3K p110alpha expressed in baculovirus using DiC8-PI(4,5)P2 as substrate after 20 mins by AlphaScreen as...				Bioorg Med Chem Lett 22: 6665-70 (2012) Article DOI: 10.1016/j.bmcl.2012.08.101 BindingDB Entry DOI: 10.7270/Q27H1KPB
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50393984 (CHEMBL2158436) Show SMILES O=c1cc(nc(NCc2cccc3ccccc23)[nH]1)N1CCOCC1 Show InChI InChI=1S/C19H20N4O2/c24-18-12-17(23-8-10-25-11-9-23)21-19(22-18)20-13-15-6-3-5-14-4-1-2-7-16(14)15/h1-7,12H,8-11,13H2,(H2,20,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PI3K p110delta				Bioorg Med Chem Lett 22: 6665-70 (2012) Article DOI: 10.1016/j.bmcl.2012.08.101 BindingDB Entry DOI: 10.7270/Q27H1KPB
					More data for this Ligand-Target Pair