BDBM50394316 CHEMBL2159371
SMILES: COc1cccc(CNS(=O)(=O)c2ccc(cc2)C(N)=N)c1
InChI Key: InChIKey=VREIYKQQHSBTGF-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prothrombin (Homo sapiens (Human)) | BDBM50394316 (CHEMBL2159371) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.23E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human thrombin using fluorogenic Cbz-Gly-Gly-Arg-NH-Mec as substrate measured over 400 secs by spectrophotometry | Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane protease serine 6 (Homo sapiens (Human)) | BDBM50394316 (CHEMBL2159371) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop... | Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD | |||||||||||
More data for this Ligand-Target Pair |