BDBM50394379 CHEMBL2159808

SMILES: CN(C)C(=O)c1cccc(CN2CCN(CC2)C(=O)n2nnc3ccccc23)c1

InChI Key: InChIKey=MYVWXEIZEIKNOS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50394379   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394379 (CHEMBL2159808) Show SMILES CN(C)C(=O)c1cccc(CN2CCN(CC2)C(=O)n2nnc3ccccc23)c1 Show InChI InChI=1S/C21H24N6O2/c1-24(2)20(28)17-7-5-6-16(14-17)15-25-10-12-26(13-11-25)21(29)27-19-9-4-3-8-18(19)22-23-27/h3-9,14H,10-13,15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50394379 (CHEMBL2159808) Show SMILES CN(C)C(=O)c1cccc(CN2CCN(CC2)C(=O)n2nnc3ccccc23)c1 Show InChI InChI=1S/C21H24N6O2/c1-24(2)20(28)17-7-5-6-16(14-17)15-25-10-12-26(13-11-25)21(29)27-19-9-4-3-8-18(19)22-23-27/h3-9,14H,10-13,15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	275	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair