BDBM50394388 CHEMBL2159799
SMILES: O=C(N1CCN(C\C=C\c2ccccc2)CC1)n1nnc2ccccc12
InChI Key: InChIKey=NUFJLSDHASNMOR-RMKNXTFCSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Monoglyceride lipase (Homo sapiens (Human)) | BDBM50394388 (CHEMBL2159799) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Jamia Hamdard (Hamdard University) Curated by ChEMBL | Assay Description Inhibition of human MAGL using 4-Nitrophenylacetate substrate incubated for 15 mins | Bioorg Med Chem Lett 24: 3986-96 (2014) Article DOI: 10.1016/j.bmcl.2014.06.029 BindingDB Entry DOI: 10.7270/Q2XP76J6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Homo sapiens (Human)) | BDBM50394388 (CHEMBL2159799) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma Curated by ChEMBL | Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil... | Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50394388 (CHEMBL2159799) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma Curated by ChEMBL | Assay Description Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq... | Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX | |||||||||||
More data for this Ligand-Target Pair |