BDBM50394691 CHEMBL2165623

SMILES: OC(=O)Cc1ccc(NC(=O)[C@H](CC2CCCC2)n2cnc(c2)C(F)(F)F)nc1

InChI Key: InChIKey=KDYJKFBLCLYERB-AWEZNQCLSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50394691   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human))	BDBM50394691 (CHEMBL2165623) Show SMILES OC(=O)Cc1ccc(NC(=O)[C@H](CC2CCCC2)n2cnc(c2)C(F)(F)F)nc1 |r| Show InChI InChI=1S/C19H21F3N4O3/c20-19(21,22)15-10-26(11-24-15)14(7-12-3-1-2-4-12)18(29)25-16-6-5-13(9-23-16)8-17(27)28/h5-6,9-12,14H,1-4,7-8H2,(H,27,28)(H,23,25,29)/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	565	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometric analysis				J Med Chem 55: 1318-33 (2012) Article DOI: 10.1021/jm2014887 BindingDB Entry DOI: 10.7270/Q2NG4RRT
					More data for this Ligand-Target Pair