BDBM50394693 CHEMBL2165621

SMILES: OC(=O)c1cccc(NC(=O)[C@H](CC2CCCC2)n2cnc(c2)C(F)(F)F)n1

InChI Key: InChIKey=WKZKRQKVEUAIAU-ZDUSSCGKSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50394693   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human))	BDBM50394693 (CHEMBL2165621) Show SMILES OC(=O)c1cccc(NC(=O)[C@H](CC2CCCC2)n2cnc(c2)C(F)(F)F)n1 |r| Show InChI InChI=1S/C18H19F3N4O3/c19-18(20,21)14-9-25(10-22-14)13(8-11-4-1-2-5-11)16(26)24-15-7-3-6-12(23-15)17(27)28/h3,6-7,9-11,13H,1-2,4-5,8H2,(H,27,28)(H,23,24,26)/t13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometric analysis				J Med Chem 55: 1318-33 (2012) Article DOI: 10.1021/jm2014887 BindingDB Entry DOI: 10.7270/Q2NG4RRT
					More data for this Ligand-Target Pair