BDBM50395011 CHEMBL2163457::US9708370, 57 CP-3(i)

SMILES: C[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)N(Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(N)=O

InChI Key: InChIKey=BGVINXUJVVAJDD-QNGZSXJXSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50395011   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin receptor (Homo sapiens (Human))	BDBM50395011 (CHEMBL2163457 | US9708370, 57 CP-3(i)) Show SMILES C[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)N(Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(N)=O |r| Show InChI InChI=1S/C40H47N11O6/c1-24(35(42)52)46-38(55)33(17-26-11-5-3-6-12-26)49-40(57)51(22-27-13-7-4-8-14-27)50-36(53)25(2)47-39(56)34(18-28-20-44-32-16-10-9-15-30(28)32)48-37(54)31(41)19-29-21-43-23-45-29/h3-16,20-21,23-25,31,33-34,44H,17-19,22,41H2,1-2H3,(H2,42,52)(H,43,45)(H,46,55)(H,47,56)(H,48,54)(H,49,57)(H,50,53)/t24-,25-,31-,33+,34+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]ghrelin expressed in in LLC-PK1 cells incubated for 1 hr by gamma counting method				J Med Chem 55: 6502-11 (2012) Article DOI: 10.1021/jm300557t BindingDB Entry DOI: 10.7270/Q22J6D00
					More data for this Ligand-Target Pair
Ghrelin receptor (Homo sapiens (Human))	BDBM50395011 (CHEMBL2163457 | US9708370, 57 CP-3(i)) Show SMILES C[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)N(Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(N)=O |r| Show InChI InChI=1S/C40H47N11O6/c1-24(35(42)52)46-38(55)33(17-26-11-5-3-6-12-26)49-40(57)51(22-27-13-7-4-8-14-27)50-36(53)25(2)47-39(56)34(18-28-20-44-32-16-10-9-15-30(28)32)48-37(54)31(41)19-29-21-43-23-45-29/h3-16,20-21,23-25,31,33-34,44H,17-19,22,41H2,1-2H3,(H2,42,52)(H,43,45)(H,46,55)(H,47,56)(H,48,54)(H,49,57)(H,50,53)/t24-,25-,31-,33+,34+/m0/s1	PDB GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
VALORISATION-RECHERCHE, LIMITED PARTNERSHIP; VALORISATION HSJ, LIMITED PARTNERSHIP US Patent					Assay Description GHS-R1a radioreceptor assay using LLCPK-1 membranes overexpressing GSH-R1a and radioiodinated (1-28) rat ghrelin as tracer.				US Patent US9708370 (2017) BindingDB Entry DOI: 10.7270/Q2XP76ZK
					More data for this Ligand-Target Pair
Platelet glycoprotein 4 (Rattus norvegicus)	BDBM50395011 (CHEMBL2163457 | US9708370, 57 CP-3(i)) Show SMILES C[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)N(Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(N)=O |r| Show InChI InChI=1S/C40H47N11O6/c1-24(35(42)52)46-38(55)33(17-26-11-5-3-6-12-26)49-40(57)51(22-27-13-7-4-8-14-27)50-36(53)25(2)47-39(56)34(18-28-20-44-32-16-10-9-15-30(28)32)48-37(54)31(41)19-29-21-43-23-45-29/h3-16,20-21,23-25,31,33-34,44H,17-19,22,41H2,1-2H3,(H2,42,52)(H,43,45)(H,46,55)(H,47,56)(H,48,54)(H,49,57)(H,50,53)/t24-,25-,31-,33+,34+/m0/s1	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Displacement of photoactivatable [125I]-Tyr-Bpa-Ala-Hexarelin from CD36 in Sprague-Dawley rat cardiac membranes incubated for 60 mins by densitometry				J Med Chem 55: 6502-11 (2012) Article DOI: 10.1021/jm300557t BindingDB Entry DOI: 10.7270/Q22J6D00
					More data for this Ligand-Target Pair