BDBM50395023 CHEMBL2163445::US9708370, 50 CP-2A(iv)

SMILES: C[C@@H](NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)NNC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O

InChI Key: InChIKey=PJGMDNIRSCUWON-GNMDYMEKSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50395023   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50395023 (CHEMBL2163445 | US9708370, 50 CP-2A(iv)) Show SMILES C[C@@H](NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)NNC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C36H48N12O6/c1-21(43-33(51)26(38)17-24-19-40-20-42-24)32(50)47-48-36(54)46-30(16-23-18-41-27-12-6-5-11-25(23)27)35(53)45-29(15-22-9-3-2-4-10-22)34(52)44-28(31(39)49)13-7-8-14-37/h2-6,9-12,18-21,26,28-30,41H,7-8,13-17,37-38H2,1H3,(H2,39,49)(H,40,42)(H,43,51)(H,44,52)(H,45,53)(H,47,50)(H2,46,48,54)/t21-,26+,28+,29-,30+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]ghrelin expressed in in LLC-PK1 cells incubated for 1 hr by gamma counting method				J Med Chem 55: 6502-11 (2012) Article DOI: 10.1021/jm300557t BindingDB Entry DOI: 10.7270/Q22J6D00
					More data for this Ligand-Target Pair
Estrogen receptor [D538G] (Homo sapiens (Human))	BDBM50395023 (CHEMBL2163445 | US9708370, 50 CP-2A(iv)) Show SMILES C[C@@H](NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)NNC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C36H48N12O6/c1-21(43-33(51)26(38)17-24-19-40-20-42-24)32(50)47-48-36(54)46-30(16-23-18-41-27-12-6-5-11-25(23)27)35(53)45-29(15-22-9-3-2-4-10-22)34(52)44-28(31(39)49)13-7-8-14-37/h2-6,9-12,18-21,26,28-30,41H,7-8,13-17,37-38H2,1H3,(H2,39,49)(H,40,42)(H,43,51)(H,44,52)(H,45,53)(H,47,50)(H2,46,48,54)/t21-,26+,28+,29-,30+/m1/s1	PDB GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
VALORISATION-RECHERCHE, LIMITED PARTNERSHIP; VALORISATION HSJ, LIMITED PARTNERSHIP US Patent					Assay Description GHS-R1a radioreceptor assay using LLCPK-1 membranes overexpressing GSH-R1a and radioiodinated (1-28) rat ghrelin as tracer.				US Patent US9708370 (2017) BindingDB Entry DOI: 10.7270/Q2XP76ZK
					More data for this Ligand-Target Pair
Platelet glycoprotein 4 (Rattus norvegicus)	BDBM50395023 (CHEMBL2163445 | US9708370, 50 CP-2A(iv)) Show SMILES C[C@@H](NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)NNC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C36H48N12O6/c1-21(43-33(51)26(38)17-24-19-40-20-42-24)32(50)47-48-36(54)46-30(16-23-18-41-27-12-6-5-11-25(23)27)35(53)45-29(15-22-9-3-2-4-10-22)34(52)44-28(31(39)49)13-7-8-14-37/h2-6,9-12,18-21,26,28-30,41H,7-8,13-17,37-38H2,1H3,(H2,39,49)(H,40,42)(H,43,51)(H,44,52)(H,45,53)(H,47,50)(H2,46,48,54)/t21-,26+,28+,29-,30+/m1/s1	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Displacement of photoactivatable [125I]-Tyr-Bpa-Ala-Hexarelin from CD36 in Sprague-Dawley rat cardiac membranes incubated for 60 mins by densitometry				J Med Chem 55: 6502-11 (2012) Article DOI: 10.1021/jm300557t BindingDB Entry DOI: 10.7270/Q22J6D00
					More data for this Ligand-Target Pair