BDBM50395056 CHEMBL2163869

SMILES: O=c1ccn(CCCCc2cnnn2CC(c2ccccc2)c2ccccc2)c(=O)[nH]1

InChI Key: InChIKey=KWPNKXVDNPZIDR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50395056   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (Homo sapiens (Human))	BDBM50395056 (CHEMBL2163869) Show SMILES O=c1ccn(CCCCc2cnnn2CC(c2ccccc2)c2ccccc2)c(=O)[nH]1 Show InChI InChI=1S/C24H25N5O2/c30-23-14-16-28(24(31)26-23)15-8-7-13-21-17-25-27-29(21)18-22(19-9-3-1-4-10-19)20-11-5-2-6-12-20/h1-6,9-12,14,16-17,22H,7-8,13,15,18H2,(H,26,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of human dUTPase assessed as reduction in [5-3H]dUMP production incubated for 15 mins by HPLC				J Med Chem 55: 6427-37 (2012) Article DOI: 10.1021/jm3004174 BindingDB Entry DOI: 10.7270/Q2XS5WJR
					More data for this Ligand-Target Pair