BDBM50395153 CHEMBL2163946

SMILES: CCC1COc2c(F)ccc3c2n1cc(C(=O)NC12CC4CC(CC(C4)C1)C2)c3=O

InChI Key: InChIKey=JOEJNYHJRTUVDE-UHFFFAOYSA-N

Data: 4 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50395153   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50395153 (CHEMBL2163946) Show SMILES CCC1COc2c(F)ccc3c2n1cc(C(=O)NC12CC4CC(CC(C4)C1)C2)c3=O |THB:23:22:19:25.24.26,23:24:21.22.27:19,26:24:21:27.18.19,26:18:21:25.23.24| Show InChI InChI=1S/C24H27FN2O3/c1-2-16-12-30-22-19(25)4-3-17-20(22)27(16)11-18(21(17)28)23(29)26-24-8-13-5-14(9-24)7-15(6-13)10-24/h3-4,11,13-16H,2,5-10,12H2,1H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in CHO cell membranes incubated for 60 mins by scintillation counting				J Med Chem 55: 6608-23 (2012) Article DOI: 10.1021/jm300763w BindingDB Entry DOI: 10.7270/Q2WS8VCX
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM50395153 (CHEMBL2163946) Show SMILES CCC1COc2c(F)ccc3c2n1cc(C(=O)NC12CC4CC(CC(C4)C1)C2)c3=O |THB:23:22:19:25.24.26,23:24:21.22.27:19,26:24:21:27.18.19,26:18:21:25.23.24| Show InChI InChI=1S/C24H27FN2O3/c1-2-16-12-30-22-19(25)4-3-17-20(22)27(16)11-18(21(17)28)23(29)26-24-8-13-5-14(9-24)7-15(6-13)10-24/h3-4,11,13-16H,2,5-10,12H2,1H3,(H,26,29)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from CB2 receptor in Sprague-Dawley rat spleen by scintillation counting				J Med Chem 55: 6608-23 (2012) Article DOI: 10.1021/jm300763w BindingDB Entry DOI: 10.7270/Q2WS8VCX
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50395153 (CHEMBL2163946) Show SMILES CCC1COc2c(F)ccc3c2n1cc(C(=O)NC12CC4CC(CC(C4)C1)C2)c3=O |THB:23:22:19:25.24.26,23:24:21.22.27:19,26:24:21:27.18.19,26:18:21:25.23.24| Show InChI InChI=1S/C24H27FN2O3/c1-2-16-12-30-22-19(25)4-3-17-20(22)27(16)11-18(21(17)28)23(29)26-24-8-13-5-14(9-24)7-15(6-13)10-24/h3-4,11,13-16H,2,5-10,12H2,1H3,(H,26,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	389	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cell membranes incubated for 90 mins by scintillation counting				J Med Chem 55: 6608-23 (2012) Article DOI: 10.1021/jm300763w BindingDB Entry DOI: 10.7270/Q2WS8VCX
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50395153 (CHEMBL2163946) Show SMILES CCC1COc2c(F)ccc3c2n1cc(C(=O)NC12CC4CC(CC(C4)C1)C2)c3=O |THB:23:22:19:25.24.26,23:24:21.22.27:19,26:24:21:27.18.19,26:18:21:25.23.24| Show InChI InChI=1S/C24H27FN2O3/c1-2-16-12-30-22-19(25)4-3-17-20(22)27(16)11-18(21(17)28)23(29)26-24-8-13-5-14(9-24)7-15(6-13)10-24/h3-4,11,13-16H,2,5-10,12H2,1H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	452	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat brain by scintillation counting				J Med Chem 55: 6608-23 (2012) Article DOI: 10.1021/jm300763w BindingDB Entry DOI: 10.7270/Q2WS8VCX
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50395153 (CHEMBL2163946) Show SMILES CCC1COc2c(F)ccc3c2n1cc(C(=O)NC12CC4CC(CC(C4)C1)C2)c3=O |THB:23:22:19:25.24.26,23:24:21.22.27:19,26:24:21:27.18.19,26:18:21:25.23.24| Show InChI InChI=1S/C24H27FN2O3/c1-2-16-12-30-22-19(25)4-3-17-20(22)27(16)11-18(21(17)28)23(29)26-24-8-13-5-14(9-24)7-15(6-13)10-24/h3-4,11,13-16H,2,5-10,12H2,1H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cell membranes assessed as inhibition of forskolin-induced cAMP accumulation				J Med Chem 55: 6608-23 (2012) Article DOI: 10.1021/jm300763w BindingDB Entry DOI: 10.7270/Q2WS8VCX
					More data for this Ligand-Target Pair