BDBM50395178 CHEMBL2163950

SMILES: O=C(NC1CCCCCC1)c1cn2C(COc3cccc(c23)c1=O)c1ccccc1

InChI Key: InChIKey=SPCANSRMNWNAPX-UHFFFAOYSA-N

Data: 4 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50395178   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50395178 (CHEMBL2163950) Show SMILES O=C(NC1CCCCCC1)c1cn2C(COc3cccc(c23)c1=O)c1ccccc1 Show InChI InChI=1S/C25H26N2O3/c28-24-19-13-8-14-22-23(19)27(21(16-30-22)17-9-4-3-5-10-17)15-20(24)25(29)26-18-11-6-1-2-7-12-18/h3-5,8-10,13-15,18,21H,1-2,6-7,11-12,16H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.810	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in CHO cell membranes incubated for 60 mins by scintillation counting				J Med Chem 55: 6608-23 (2012) Article DOI: 10.1021/jm300763w BindingDB Entry DOI: 10.7270/Q2WS8VCX
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM50395178 (CHEMBL2163950) Show SMILES O=C(NC1CCCCCC1)c1cn2C(COc3cccc(c23)c1=O)c1ccccc1 Show InChI InChI=1S/C25H26N2O3/c28-24-19-13-8-14-22-23(19)27(21(16-30-22)17-9-4-3-5-10-17)15-20(24)25(29)26-18-11-6-1-2-7-12-18/h3-5,8-10,13-15,18,21H,1-2,6-7,11-12,16H2,(H,26,29)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from CB2 receptor in Sprague-Dawley rat spleen by scintillation counting				J Med Chem 55: 6608-23 (2012) Article DOI: 10.1021/jm300763w BindingDB Entry DOI: 10.7270/Q2WS8VCX
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50395178 (CHEMBL2163950) Show SMILES O=C(NC1CCCCCC1)c1cn2C(COc3cccc(c23)c1=O)c1ccccc1 Show InChI InChI=1S/C25H26N2O3/c28-24-19-13-8-14-22-23(19)27(21(16-30-22)17-9-4-3-5-10-17)15-20(24)25(29)26-18-11-6-1-2-7-12-18/h3-5,8-10,13-15,18,21H,1-2,6-7,11-12,16H2,(H,26,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cell membranes incubated for 90 mins by scintillation counting				J Med Chem 55: 6608-23 (2012) Article DOI: 10.1021/jm300763w BindingDB Entry DOI: 10.7270/Q2WS8VCX
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50395178 (CHEMBL2163950) Show SMILES O=C(NC1CCCCCC1)c1cn2C(COc3cccc(c23)c1=O)c1ccccc1 Show InChI InChI=1S/C25H26N2O3/c28-24-19-13-8-14-22-23(19)27(21(16-30-22)17-9-4-3-5-10-17)15-20(24)25(29)26-18-11-6-1-2-7-12-18/h3-5,8-10,13-15,18,21H,1-2,6-7,11-12,16H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	372	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat brain by scintillation counting				J Med Chem 55: 6608-23 (2012) Article DOI: 10.1021/jm300763w BindingDB Entry DOI: 10.7270/Q2WS8VCX
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50395178 (CHEMBL2163950) Show SMILES O=C(NC1CCCCCC1)c1cn2C(COc3cccc(c23)c1=O)c1ccccc1 Show InChI InChI=1S/C25H26N2O3/c28-24-19-13-8-14-22-23(19)27(21(16-30-22)17-9-4-3-5-10-17)15-20(24)25(29)26-18-11-6-1-2-7-12-18/h3-5,8-10,13-15,18,21H,1-2,6-7,11-12,16H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.23	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cell membranes assessed as inhibition of forskolin-induced cAMP accumulation				J Med Chem 55: 6608-23 (2012) Article DOI: 10.1021/jm300763w BindingDB Entry DOI: 10.7270/Q2WS8VCX
					More data for this Ligand-Target Pair