BDBM50395317 CHEMBL2164003

SMILES: CCCC1CC(=O)c2cc(Cl)cc(Br)c2O1

InChI Key: InChIKey=PLMKQLJYZZAIHG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50395317   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human))	BDBM50395317 (CHEMBL2164003) Show SMILES CCCC1CC(=O)c2cc(Cl)cc(Br)c2O1 Show InChI InChI=1S/C12H12BrClO2/c1-2-3-8-6-11(15)9-4-7(14)5-10(13)12(9)16-8/h4-5,8H,2-3,6H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Gothenburg Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged SIRT2 preincubated for 5 mins measured after 1 hr by Fluor de Lys-based fluorescence assay				J Med Chem 55: 7104-13 (2012) Article DOI: 10.1021/jm3005288 BindingDB Entry DOI: 10.7270/Q2VT1T6N
					More data for this Ligand-Target Pair