BDBM50395544 CHEMBL2164788
SMILES: CCO\N=C1/C=C(CCC1F)C#Cc1ccccn1
InChI Key: InChIKey=OXITTWFVOBVMDI-OBGWFSINSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Metabotropic glutamate receptor (Rattus norvegicus (Rat)) | BDBM50395544 (CHEMBL2164788) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 31.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Technology (ETH) Zurich Curated by ChEMBL | Assay Description Displacement of [3H]-ABP688 from mGluR5 receptor in Sprague-Dawley rat brain after 45 mins by beta counting | J Med Chem 55: 7154-62 (2012) Article DOI: 10.1021/jm300648b BindingDB Entry DOI: 10.7270/Q2ST7QZX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor (Rattus norvegicus (Rat)) | BDBM50395544 (CHEMBL2164788) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a |
Institute of Technology (ETH) Zurich Curated by ChEMBL | Assay Description Binding affinity to mGluR5 receptor in Sprague-Dawley rat brain by beta counting | J Med Chem 55: 7154-62 (2012) Article DOI: 10.1021/jm300648b BindingDB Entry DOI: 10.7270/Q2ST7QZX | |||||||||||
More data for this Ligand-Target Pair |