BDBM50395548 CHEMBL2164783

SMILES: CO\N=C1\C=C(CCC1F)C#Cc1ccccn1

InChI Key: InChIKey=JHAYBUSYQMATNA-VKAVYKQESA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50395548   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50395548 (CHEMBL2164783) Show SMILES CO\N=C1\C=C(CCC1F)C#Cc1ccccn1 |c:4| Show InChI InChI=1S/C14H13FN2O/c1-18-17-14-10-11(6-8-13(14)15)5-7-12-4-2-3-9-16-12/h2-4,9-10,13H,6,8H2,1H3/b17-14-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology (ETH) Zurich Curated by ChEMBL					Assay Description Displacement of [3H]-ABP688 from mGluR5 receptor in Sprague-Dawley rat brain after 45 mins by beta counting				J Med Chem 55: 7154-62 (2012) Article DOI: 10.1021/jm300648b BindingDB Entry DOI: 10.7270/Q2ST7QZX
					More data for this Ligand-Target Pair