BDBM50395748 CHEMBL2164827

SMILES: CN1CCN(CC(=O)NC2(C(=O)Nc3cc(Cl)ccc23)c2ccc(Cl)cc2)CC1

InChI Key: InChIKey=UVEJEVSQFOAZAP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50395748   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin receptor (Homo sapiens (Human))	BDBM50395748 (CHEMBL2164827) Show SMILES CN1CCN(CC(=O)NC2(C(=O)Nc3cc(Cl)ccc23)c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C21H22Cl2N4O2/c1-26-8-10-27(11-9-26)13-19(28)25-21(14-2-4-15(22)5-3-14)17-7-6-16(23)12-18(17)24-20(21)29/h2-7,12H,8-11,13H2,1H3,(H,24,29)(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Research Curated by ChEMBL					Assay Description Antagonist activity at human GHSR1 expressed in CHO-CREluc cells after 4 hrs by Luciferase reporter assay				Bioorg Med Chem 20: 5623-36 (2012) Article DOI: 10.1016/j.bmc.2012.07.018 BindingDB Entry DOI: 10.7270/Q2HD7WS4
					More data for this Ligand-Target Pair