BDBM50395759 CHEMBL2164822

SMILES: Cc1cc2c(NC(=O)C2(NC(=O)CN2CCN(CC2)c2ccncc2)c2ccc(Cl)cc2)cc1Cl

InChI Key: InChIKey=JGRCHQARPTVWOY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50395759   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin receptor (Homo sapiens (Human))	BDBM50395759 (CHEMBL2164822) Show SMILES Cc1cc2c(NC(=O)C2(NC(=O)CN2CCN(CC2)c2ccncc2)c2ccc(Cl)cc2)cc1Cl Show InChI InChI=1S/C26H25Cl2N5O2/c1-17-14-21-23(15-22(17)28)30-25(35)26(21,18-2-4-19(27)5-3-18)31-24(34)16-32-10-12-33(13-11-32)20-6-8-29-9-7-20/h2-9,14-15H,10-13,16H2,1H3,(H,30,35)(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Research Curated by ChEMBL					Assay Description Antagonist activity at human GHSR1 expressed in CHO-CREluc cells after 4 hrs by Luciferase reporter assay				Bioorg Med Chem 20: 5623-36 (2012) Article DOI: 10.1016/j.bmc.2012.07.018 BindingDB Entry DOI: 10.7270/Q2HD7WS4
					More data for this Ligand-Target Pair