BDBM50395773 CHEMBL2164835

SMILES: COc1ccc(cc1)C1(NC(=O)CN2CCN(C)CC2)C(=O)Nc2cc(Cl)c(C)cc12

InChI Key: InChIKey=AWHFSCLBUGXRCU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50395773   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin receptor (Homo sapiens (Human))	BDBM50395773 (CHEMBL2164835) Show SMILES COc1ccc(cc1)C1(NC(=O)CN2CCN(C)CC2)C(=O)Nc2cc(Cl)c(C)cc12 Show InChI InChI=1S/C23H27ClN4O3/c1-15-12-18-20(13-19(15)24)25-22(30)23(18,16-4-6-17(31-3)7-5-16)26-21(29)14-28-10-8-27(2)9-11-28/h4-7,12-13H,8-11,14H2,1-3H3,(H,25,30)(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	525	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Research Curated by ChEMBL					Assay Description Antagonist activity at human GHSR1 expressed in CHO-CREluc cells after 4 hrs by Luciferase reporter assay				Bioorg Med Chem 20: 5623-36 (2012) Article DOI: 10.1016/j.bmc.2012.07.018 BindingDB Entry DOI: 10.7270/Q2HD7WS4
					More data for this Ligand-Target Pair