BDBM50395780 CHEMBL2164855

SMILES: COc1ncc(cc1NC(=O)[C@H](Cc1ccccc1)NC1(CC1)c1ccccn1)-c1ccncc1

InChI Key: InChIKey=IBYCTVAMYWOPHB-QHCPKHFHSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50395780   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Probable G-protein coupled receptor 142 (Homo sapiens (Human))	BDBM50395780 (CHEMBL2164855) Show SMILES COc1ncc(cc1NC(=O)[C@H](Cc1ccccc1)NC1(CC1)c1ccccn1)-c1ccncc1 |r| Show InChI InChI=1S/C28H27N5O2/c1-35-27-24(18-22(19-31-27)21-10-15-29-16-11-21)32-26(34)23(17-20-7-3-2-4-8-20)33-28(12-13-28)25-9-5-6-14-30-25/h2-11,14-16,18-19,23,33H,12-13,17H2,1H3,(H,32,34)/t23-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation after 1 hr by scintillation counting				Bioorg Med Chem Lett 22: 6218-23 (2012) Article DOI: 10.1016/j.bmcl.2012.08.015 BindingDB Entry DOI: 10.7270/Q2CN751R
					More data for this Ligand-Target Pair