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SMILES: CCN(CCO)C(=O)c1cc2cc(OC)cnn2c1-c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=KCACIGOHNKGOAR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50395951   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50395951
PNG
(CHEMBL2164563)
Show SMILES CCN(CCO)C(=O)c1cc2cc(OC)cnn2c1-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C20H20F3N3O3/c1-3-25(7-8-27)19(28)17-11-15-10-16(29-2)12-24-26(15)18(17)13-5-4-6-14(9-13)20(21,22)23/h4-6,9-12,27H,3,7-8H2,1-2H3
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n/an/a 5.01E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 expressed in CHO cells by IonWorks assay

Bioorg Med Chem Lett 22: 6888-95 (2012)


Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63
More data for this
Ligand-Target Pair