BDBM50396033 CHEMBL2169982

SMILES: COc1cc2CCN(C(=O)Nc3cc(cc(c3)C(F)(F)F)-c3cccnc3)c2cc1C(F)(F)F

InChI Key: InChIKey=YAZJLXFAUHRWKL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50396033   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50396033 (CHEMBL2169982) Show SMILES COc1cc2CCN(C(=O)Nc3cc(cc(c3)C(F)(F)F)-c3cccnc3)c2cc1C(F)(F)F Show InChI InChI=1S/C23H17F6N3O2/c1-34-20-9-13-4-6-32(19(13)11-18(20)23(27,28)29)21(33)31-17-8-15(14-3-2-5-30-12-14)7-16(10-17)22(24,25)26/h2-3,5,7-12H,4,6H2,1H3,(H,31,33)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...				ACS Med Chem Lett 3: 373-377 (2012) Article DOI: 10.1021/ml300008j BindingDB Entry DOI: 10.7270/Q2PZ59X6
					More data for this Ligand-Target Pair