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SMILES: CN1CCN(CC1)c1cc2N(CCc2cc1Cl)C(=O)Nc1cc(OC(F)(F)F)cc(c1)-c1cccnc1

InChI Key: InChIKey=QRIJCCNAKWXNBU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50396035   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50396035
PNG
(CHEMBL2169981)
Show SMILES CN1CCN(CC1)c1cc2N(CCc2cc1Cl)C(=O)Nc1cc(OC(F)(F)F)cc(c1)-c1cccnc1
Show InChI InChI=1S/C26H25ClF3N5O2/c1-33-7-9-34(10-8-33)24-15-23-17(13-22(24)27)4-6-35(23)25(36)32-20-11-19(18-3-2-5-31-16-18)12-21(14-20)37-26(28,29)30/h2-3,5,11-16H,4,6-10H2,1H3,(H,32,36)
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Similars
Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...

ACS Med Chem Lett 3: 373-377 (2012)


Article DOI: 10.1021/ml300008j
BindingDB Entry DOI: 10.7270/Q2PZ59X6
More data for this
Ligand-Target Pair