BDBM50396047 CHEMBL482551

SMILES: O=C(Nc1ccccc1-c1nc2ccccc2[nH]1)c1cnc2ccccc2n1

InChI Key: InChIKey=QNTKWFIPQIZZSW-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50396047   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-Dependent Deacetylase Sirtuin-1 (Homo sapiens (Human))	BDBM50396047 (CHEMBL482551) Show SMILES O=C(Nc1ccccc1-c1nc2ccccc2[nH]1)c1cnc2ccccc2n1 Show InChI InChI=1S/C22H15N5O/c28-22(20-13-23-16-9-3-4-10-17(16)24-20)27-15-8-2-1-7-14(15)21-25-18-11-5-6-12-19(18)26-21/h1-13H,(H,25,26)(H,27,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
Sirtris, A GSK Company Curated by ChEMBL					Assay Description Activation of SIRT1				J Med Chem 54: 417-32 (2011) Article DOI: 10.1021/jm100861p BindingDB Entry DOI: 10.7270/Q25X2B28
					More data for this Ligand-Target Pair