BDBM50396049 CHEMBL473881

SMILES: COc1ccc(cc1OC)C(=O)Nc1ccccc1-c1nc2ncccc2o1

InChI Key: InChIKey=AYIAGTDESMAUEG-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50396049   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-Dependent Deacetylase Sirtuin-1 (Homo sapiens (Human))	BDBM50396049 (CHEMBL473881) Show SMILES COc1ccc(cc1OC)C(=O)Nc1ccccc1-c1nc2ncccc2o1 Show InChI InChI=1S/C21H17N3O4/c1-26-16-10-9-13(12-18(16)27-2)20(25)23-15-7-4-3-6-14(15)21-24-19-17(28-21)8-5-11-22-19/h3-12H,1-2H3,(H,23,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a
Sirtris, A GSK Company Curated by ChEMBL					Assay Description Activation of SIRT1				J Med Chem 54: 417-32 (2011) Article DOI: 10.1021/jm100861p BindingDB Entry DOI: 10.7270/Q25X2B28
					More data for this Ligand-Target Pair