null

SMILES: CNc1nc(Nc2ccccc2OC)ncc1Cl

InChI Key: InChIKey=AGIGZRMODPEFNF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50396155   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50396155 (CHEMBL2171738) Show SMILES CNc1nc(Nc2ccccc2OC)ncc1Cl Show InChI InChI=1S/C12H13ClN4O/c1-14-11-8(13)7-15-12(17-11)16-9-5-3-4-6-10(9)18-2/h3-7H,1-2H3,(H2,14,15,16,17)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of LRRK2				J Med Chem 55: 5536-45 (2012) Article DOI: 10.1021/jm300452p BindingDB Entry DOI: 10.7270/Q2RR20CQ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50396155 (CHEMBL2171738) Show SMILES CNc1nc(Nc2ccccc2OC)ncc1Cl Show InChI InChI=1S/C12H13ClN4O/c1-14-11-8(13)7-15-12(17-11)16-9-5-3-4-6-10(9)18-2/h3-7H,1-2H3,(H2,14,15,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2				J Med Chem 55: 5536-45 (2012) Article DOI: 10.1021/jm300452p BindingDB Entry DOI: 10.7270/Q2RR20CQ
					More data for this Ligand-Target Pair