null

SMILES: CNc1nc(Nc2ccc(cc2)C(=O)N2CCOCC2)ncc1Cl

InChI Key: InChIKey=AMQCBROKDRYSQO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50396158   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50396158 (CHEMBL2171748) Show SMILES CNc1nc(Nc2ccc(cc2)C(=O)N2CCOCC2)ncc1Cl Show InChI InChI=1S/C16H18ClN5O2/c1-18-14-13(17)10-19-16(21-14)20-12-4-2-11(3-5-12)15(23)22-6-8-24-9-7-22/h2-5,10H,6-9H2,1H3,(H2,18,19,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of LRRK2				J Med Chem 55: 5536-45 (2012) Article DOI: 10.1021/jm300452p BindingDB Entry DOI: 10.7270/Q2RR20CQ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50396158 (CHEMBL2171748) Show SMILES CNc1nc(Nc2ccc(cc2)C(=O)N2CCOCC2)ncc1Cl Show InChI InChI=1S/C16H18ClN5O2/c1-18-14-13(17)10-19-16(21-14)20-12-4-2-11(3-5-12)15(23)22-6-8-24-9-7-22/h2-5,10H,6-9H2,1H3,(H2,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2				J Med Chem 55: 5536-45 (2012) Article DOI: 10.1021/jm300452p BindingDB Entry DOI: 10.7270/Q2RR20CQ
					More data for this Ligand-Target Pair