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BDBM50396227 CHEMBL2172185

SMILES: CNc1nn2c3CCNCc3cnc2c1S(=O)(=O)c1ccccc1

InChI Key: InChIKey=QHHSRUJIHHZGHA-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50396227   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50396227
PNG
(CHEMBL2172185)
Show SMILES CNc1nn2c3CCNCc3cnc2c1S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C16H17N5O2S/c1-17-15-14(24(22,23)12-5-3-2-4-6-12)16-19-10-11-9-18-8-7-13(11)21(16)20-15/h2-6,10,18H,7-9H2,1H3,(H,17,20)
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PC cid
PC sid
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Similars

Article
PubMed
1.90n/an/an/an/an/an/an/an/a



Chemical Diversity Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant 5HT6 receptor expressed in HE293 cells assessed as inhibition of serotonin-induced cAMP accumulation after 2...


Bioorg Med Chem Lett 22: 4273-80 (2012)


Article DOI: 10.1016/j.bmcl.2012.05.036
BindingDB Entry DOI: 10.7270/Q2VH5PZ8
More data for this
Ligand-Target Pair