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SMILES: CN1CCc2c(C1)cnc1c(c(C)nn21)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=HXWBAPBYAWNJPM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50396233   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50396233 (CHEMBL2172182 | US8569318, 1.1(3)) Show SMILES CN1CCc2c(C1)cnc1c(c(C)nn21)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H18N4O2S/c1-12-16(24(22,23)14-6-4-3-5-7-14)17-18-10-13-11-20(2)9-8-15(13)21(17)19-12/h3-7,10H,8-9,11H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	60	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Activity test of serotonin 5-HT6 receptor antagonists of the general formulas 1, 2 in the setting of competitive binding to serotonin 5-HT6 receptors...				US Patent US8569318 (2013) BindingDB Entry DOI: 10.7270/Q2JH3JT8
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50396233 (CHEMBL2172182 | US8569318, 1.1(3)) Show SMILES CN1CCc2c(C1)cnc1c(c(C)nn21)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H18N4O2S/c1-12-16(24(22,23)14-6-4-3-5-7-14)17-18-10-13-11-20(2)9-8-15(13)21(17)19-12/h3-7,10H,8-9,11H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]lysergic acid diethylamide from human recombinant 5HT6 receptor expressed in HeLa cells after 120 mins				Bioorg Med Chem Lett 22: 4273-80 (2012) Article DOI: 10.1016/j.bmcl.2012.05.036 BindingDB Entry DOI: 10.7270/Q2VH5PZ8
					More data for this Ligand-Target Pair