BDBM50396333 CHEMBL2170036

SMILES: Clc1cccc(c1)C(Nc1ccnc2cc(Cl)ccc12)c1ccc(CN2CCNCC2)cc1

InChI Key: InChIKey=KCWHLHQCEFYQKX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50396333   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chloroquine resistance transporter (Plasmodium falciparum)	BDBM50396333 (CHEMBL2170036) Show SMILES Clc1cccc(c1)C(Nc1ccnc2cc(Cl)ccc12)c1ccc(CN2CCNCC2)cc1 Show InChI InChI=1S/C27H26Cl2N4/c28-22-3-1-2-21(16-22)27(32-25-10-11-31-26-17-23(29)8-9-24(25)26)20-6-4-19(5-7-20)18-33-14-12-30-13-15-33/h1-11,16-17,27,30H,12-15,18H2,(H,31,32)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 CRT expressed in Xenopus laevis oocyte assessed as inhibition of [3H]chloroquine uptake...				J Med Chem 55: 6948-67 (2012) Article DOI: 10.1021/jm300802s BindingDB Entry DOI: 10.7270/Q2319X1X
					More data for this Ligand-Target Pair