BDBM50396589 CHEMBL2171916

SMILES: CN1c2ccc(cc2C(=C)c2ccccc2C1=O)C(C)(C)C

InChI Key: InChIKey=NNOHGGBPJHNYNA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50396589   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50396589 (CHEMBL2171916) Show SMILES CN1c2ccc(cc2C(=C)c2ccccc2C1=O)C(C)(C)C Show InChI InChI=1S/C20H21NO/c1-13-15-8-6-7-9-16(15)19(22)21(5)18-11-10-14(12-17(13)18)20(2,3)4/h6-12H,1H2,2-5H3	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Transactivational antagonist activity at human LXRalpha transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced luci...				J Med Chem 55: 7360-77 (2012) Article DOI: 10.1021/jm3002394 BindingDB Entry DOI: 10.7270/Q2NV9KCH
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50396589 (CHEMBL2171916) Show SMILES CN1c2ccc(cc2C(=C)c2ccccc2C1=O)C(C)(C)C Show InChI InChI=1S/C20H21NO/c1-13-15-8-6-7-9-16(15)19(22)21(5)18-11-10-14(12-17(13)18)20(2,3)4/h6-12H,1H2,2-5H3	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Transactivational antagonist activity at human LXRbeta transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced lucif...				J Med Chem 55: 7360-77 (2012) Article DOI: 10.1021/jm3002394 BindingDB Entry DOI: 10.7270/Q2NV9KCH
					More data for this Ligand-Target Pair