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BDBM50396910 CHEMBL2170698

SMILES: CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@@H](N)CCCCN)C(N)=O

InChI Key: InChIKey=MOWXKXPLSYMKPF-CBDSZOPFSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50396910   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ghrelin receptor


(Homo sapiens (Human))		BDBM50396910
PNG
(CHEMBL2170698)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@@H](N)CCCCN)C(N)=O |r|
Show InChI InChI=1S/C53H69N9O6/c1-33(2)27-43(48(56)63)58-50(65)44(28-34(3)4)60-53(68)47(31-39-32-57-42-21-12-11-19-40(39)42)62-52(67)46(29-35-15-7-5-8-16-35)61-51(66)45(59-49(64)41(55)20-13-14-26-54)30-36-22-24-38(25-23-36)37-17-9-6-10-18-37/h5-12,15-19,21-25,32-34,41,43-47,57H,13-14,20,26-31,54-55H2,1-4H3,(H2,56,63)(H,58,65)(H,59,64)(H,60,68)(H,61,66)(H,62,67)/t41-,43-,44-,45+,46-,47+/m0/s1
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Similars
Article
PubMed
n/an/an/an/a 184n/an/an/an/a



Universit£t Leipzig

Curated by ChEMBL


Assay Description
Inverse agonist activity at human ghrelin receptor expressed in COS 7 cells using [2-3H]myo-inositol by inositol triphosphate turnover assay

J Med Chem 55: 7437-49 (2012)


Article DOI: 10.1021/jm300414b
BindingDB Entry DOI: 10.7270/Q26M37Z8
More data for this
Ligand-Target Pair