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BDBM50396912 CHEMBL2170784

SMILES: CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(=O)[C@@H](N)CCCCN)C(N)=O

InChI Key: InChIKey=QTUCUNDJYOCBSE-MHRDGXECSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50396912   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ghrelin receptor


(Homo sapiens (Human))		BDBM50396912
PNG
(CHEMBL2170784)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(=O)[C@@H](N)CCCCN)C(N)=O |r|
Show InChI InChI=1S/C51H67N9O6/c1-31(2)24-41(46(54)61)56-48(63)42(25-32(3)4)58-51(66)45(29-37-30-55-40-20-11-10-18-38(37)40)60-49(64)43(27-33-14-6-5-7-15-33)59-50(65)44(57-47(62)39(53)19-12-13-23-52)28-34-21-22-35-16-8-9-17-36(35)26-34/h5-11,14-18,20-22,26,30-32,39,41-45,55H,12-13,19,23-25,27-29,52-53H2,1-4H3,(H2,54,61)(H,56,63)(H,57,62)(H,58,66)(H,59,65)(H,60,64)/t39-,41-,42-,43-,44+,45+/m0/s1
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Similars
Article
PubMed
n/an/an/an/a 161n/an/an/an/a



Universit£t Leipzig

Curated by ChEMBL


Assay Description
Inverse agonist activity at human ghrelin receptor expressed in COS 7 cells using [2-3H]myo-inositol by inositol triphosphate turnover assay

J Med Chem 55: 7437-49 (2012)


Article DOI: 10.1021/jm300414b
BindingDB Entry DOI: 10.7270/Q26M37Z8
More data for this
Ligand-Target Pair