BDBM50397040 CHEMBL2171200

SMILES: CCCn1c(=O)nc2oc3ccccc3cc2c1=O

InChI Key: InChIKey=JAGRBAMWVKDHKB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50397040   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-Dependent Deacetylase Sirtuin-1 (Homo sapiens (Human))	BDBM50397040 (CHEMBL2171200) Show SMILES CCCn1c(=O)nc2oc3ccccc3cc2c1=O Show InChI InChI=1S/C14H12N2O3/c1-2-7-16-13(17)10-8-9-5-3-4-6-11(9)19-12(10)15-14(16)18/h3-6,8H,2,7H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT1 expressed in Escherichia coli cells using acetylated Lys side chain amino acids 379-382 (Arg-His-Lys-Lys(Ac)) p...				J Med Chem 55: 8193-7 (2012) Article DOI: 10.1021/jm301115r BindingDB Entry DOI: 10.7270/Q2JW8G0C
					More data for this Ligand-Target Pair
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human))	BDBM50397040 (CHEMBL2171200) Show SMILES CCCn1c(=O)nc2oc3ccccc3cc2c1=O Show InChI InChI=1S/C14H12N2O3/c1-2-7-16-13(17)10-8-9-5-3-4-6-11(9)19-12(10)15-14(16)18/h3-6,8H,2,7H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.99E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT2 expressed in Escherichia coli cells using acetylated Lys side chain amino acids 379-382 (Arg-His-Lys-Lys(Ac)) p...				J Med Chem 55: 8193-7 (2012) Article DOI: 10.1021/jm301115r BindingDB Entry DOI: 10.7270/Q2JW8G0C
					More data for this Ligand-Target Pair