BDBM50397611 CHEMBL2181703

SMILES: COc1ccc(cc1S(=O)(=O)N(C)C1CCCC1)-c1c(C)noc1C

InChI Key: InChIKey=ONUKWYBZXUKVSG-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50397611   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50397611 (CHEMBL2181703) Show SMILES COc1ccc(cc1S(=O)(=O)N(C)C1CCCC1)-c1c(C)noc1C Show InChI InChI=1S/C18H24N2O4S/c1-12-18(13(2)24-19-12)14-9-10-16(23-4)17(11-14)25(21,22)20(3)15-7-5-6-8-15/h9-11,15H,5-8H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of His6-tagged BRD4-BD12 expressed in Escherichia coli assessed as inhibition of binding to SGRG-K(Ac)-GG-K(Ac)-GLG-K(Ac)-GGA-K(Ac)-RHGSGS...				J Med Chem 55: 587-96 (2012) Article DOI: 10.1021/jm201283q BindingDB Entry DOI: 10.7270/Q22R3SSS
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM50397611 (CHEMBL2181703) Show SMILES COc1ccc(cc1S(=O)(=O)N(C)C1CCCC1)-c1c(C)noc1C Show InChI InChI=1S/C18H24N2O4S/c1-12-18(13(2)24-19-12)14-9-10-16(23-4)17(11-14)25(21,22)20(3)15-7-5-6-8-15/h9-11,15H,5-8H2,1-4H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of His6-tagged BRD2 expressed in Escherichia coli assessed as inhibition of binding to SGRG-K(Ac)-GG-K(Ac)-GLG-K(Ac)-GGA-K(Ac)-RHGSGSK-bio...				J Med Chem 55: 587-96 (2012) Article DOI: 10.1021/jm201283q BindingDB Entry DOI: 10.7270/Q22R3SSS
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM50397611 (CHEMBL2181703) Show SMILES COc1ccc(cc1S(=O)(=O)N(C)C1CCCC1)-c1c(C)noc1C Show InChI InChI=1S/C18H24N2O4S/c1-12-18(13(2)24-19-12)14-9-10-16(23-4)17(11-14)25(21,22)20(3)15-7-5-6-8-15/h9-11,15H,5-8H2,1-4H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of His6-tagged BRD3 expressed in Escherichia coli assessed as inhibition of binding to SGRG-K(Ac)-GG-K(Ac)-GLG-K(Ac)-GGA-K(Ac)-RHGSGSK-bio...				J Med Chem 55: 587-96 (2012) Article DOI: 10.1021/jm201283q BindingDB Entry DOI: 10.7270/Q22R3SSS
					More data for this Ligand-Target Pair