BDBM50398166 CHEMBL2182071

SMILES: O=C(Nc1cccc(Nc2ccc3c(CCc4ccccc4C3=O)c2)c1)c1ccoc1

InChI Key: InChIKey=OVRCQWCVSWDVMT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50398166   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398166 (CHEMBL2182071) Show SMILES O=C(Nc1cccc(Nc2ccc3c(CCc4ccccc4C3=O)c2)c1)c1ccoc1 Show InChI InChI=1S/C26H20N2O3/c29-25-23-7-2-1-4-17(23)8-9-18-14-22(10-11-24(18)25)27-20-5-3-6-21(15-20)28-26(30)19-12-13-31-16-19/h1-7,10-16,27H,8-9H2,(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair