BDBM50398237 CHEMBL2177249
SMILES: CCCCCc1cc(OC)c2cc(Cc3cccc(OC)c3)c(=O)oc2c1
InChI Key: InChIKey=FUDLPNVYTSNVGM-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50398237 (CHEMBL2177249) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 45 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Displacement of [3H]CP55,940 from human CB1 receptor expressed in CHO cells after 2 hrs by liquid scintillation counter | J Med Chem 55: 7967-77 (2012) Article DOI: 10.1021/jm3008213 BindingDB Entry DOI: 10.7270/Q2JM2BRJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50398237 (CHEMBL2177249) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 143 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Displacement of [3H]CP55,940 from human CB2 receptor expressed in CHO cells after 2 hrs by liquid scintillation counter | J Med Chem 55: 7967-77 (2012) Article DOI: 10.1021/jm3008213 BindingDB Entry DOI: 10.7270/Q2JM2BRJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50398237 (CHEMBL2177249) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 430 | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation using [3H]-cAMP after ... | J Med Chem 55: 7967-77 (2012) Article DOI: 10.1021/jm3008213 BindingDB Entry DOI: 10.7270/Q2JM2BRJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 55 (Homo sapiens (Human)) | BDBM50398237 (CHEMBL2177249) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Antagonist activity at human GPR55 transfected in CHO cells assessed as inhibition of LPI-induced beta-arrestin recruitment incubated 60 mins prior t... | J Med Chem 56: 4798-810 (2013) Article DOI: 10.1021/jm4005175 BindingDB Entry DOI: 10.7270/Q2GM88QX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-arachidonyl glycine receptor (Homo sapiens (Human)) | BDBM50398237 (CHEMBL2177249) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta... | J Med Chem 56: 4798-810 (2013) Article DOI: 10.1021/jm4005175 BindingDB Entry DOI: 10.7270/Q2GM88QX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 55 (Homo sapiens (Human)) | BDBM50398237 (CHEMBL2177249) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.00794 | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Antagonist activity at human GPR55 transfected in CHO cells assessed as inhibition of LPI-induced beta-arrestin recruitment incubated 60 mins prior t... | J Med Chem 56: 4798-810 (2013) Article DOI: 10.1021/jm4005175 BindingDB Entry DOI: 10.7270/Q2GM88QX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50398237 (CHEMBL2177249) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 92 | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation using [3H]-cAMP after ... | J Med Chem 55: 7967-77 (2012) Article DOI: 10.1021/jm3008213 BindingDB Entry DOI: 10.7270/Q2JM2BRJ | |||||||||||
More data for this Ligand-Target Pair |