BDBM50398332 CHEMBL2177351

SMILES: Oc1ccc(Br)cc1\C=C1/Oc2ccccc2C1=O

InChI Key: InChIKey=AUKZKXDRMUZVNF-ZSOIEALJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50398332   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-Dependent Deacetylase Sirtuin-1 (Homo sapiens (Human))	BDBM50398332 (CHEMBL2177351) Show SMILES Oc1ccc(Br)cc1\C=C1/Oc2ccccc2C1=O Show InChI InChI=1S/C15H9BrO3/c16-10-5-6-12(17)9(7-10)8-14-15(18)11-3-1-2-4-13(11)19-14/h1-8,17H/b14-8-	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Hyderabad Campus Curated by ChEMBL					Assay Description Inhibition of full length recombinant human SIRT1 expressed in Escherichia coli BL21 (DE3) PLysS using Fluor-de-Lys as substrate by fluorimetric assa...				Bioorg Med Chem Lett 22: 6160-5 (2012) Article DOI: 10.1016/j.bmcl.2012.08.017 BindingDB Entry DOI: 10.7270/Q2CV4JWF
					More data for this Ligand-Target Pair