BDBM50398469 CHEMBL2179123

SMILES: Fc1ccc(cc1)-c1[nH]c(nc1-c1ncnc2[nH]ccc12)-c1ccccc1

InChI Key: InChIKey=FMVKIPNKXJXTQK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50398469   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398469 (CHEMBL2179123) Show SMILES Fc1ccc(cc1)-c1[nH]c(nc1-c1ncnc2[nH]ccc12)-c1ccccc1 Show InChI InChI=1S/C21H14FN5/c22-15-8-6-13(7-9-15)17-19(18-16-10-11-23-21(16)25-12-24-18)27-20(26-17)14-4-2-1-3-5-14/h1-12H,(H,26,27)(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tuebingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK				J Med Chem 55: 8429-39 (2012) Article DOI: 10.1021/jm300852w BindingDB Entry DOI: 10.7270/Q2765GGT
					More data for this Ligand-Target Pair