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SMILES: CC(C)(C)c1cc(NC(=O)CCCN2CCCCC2)n[nH]1

InChI Key: InChIKey=OGPREQIZGSIMHW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50399291   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-7


(Rattus norvegicus (Rat))		BDBM50399291
PNG
(CHEMBL2180839)
Show SMILES CC(C)(C)c1cc(NC(=O)CCCN2CCCCC2)n[nH]1
Show InChI InChI=1S/C16H28N4O/c1-16(2,3)13-12-14(19-18-13)17-15(21)8-7-11-20-9-5-4-6-10-20/h12H,4-11H2,1-3H3,(H2,17,18,19,21)
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Article
PubMed
n/an/an/an/a>3.16E+4n/an/an/an/a



Siena Biotech SpA

Curated by ChEMBL


Assay Description
Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells assessed as stimulation of calcium flux by FLIPR

J Med Chem 55: 10277-81 (2012)


Article DOI: 10.1021/jm3013568
BindingDB Entry DOI: 10.7270/Q2DJ5GRD
More data for this
Ligand-Target Pair