BDBM50399545 CHEMBL2180902

SMILES: CS(=O)(=O)c1ccccc1C(=O)N1CCC(CC1)N(C1CC1)S(=O)(=O)c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=LICNHLYXAUMODF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50399545   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50399545 (CHEMBL2180902) Show SMILES CS(=O)(=O)c1ccccc1C(=O)N1CCC(CC1)N(C1CC1)S(=O)(=O)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C23H25F3N2O5S2/c1-34(30,31)21-8-3-2-7-20(21)22(29)27-13-11-18(12-14-27)28(17-9-10-17)35(32,33)19-6-4-5-16(15-19)23(24,25)26/h2-8,15,17-18H,9-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Cav2.2 expressed HEK293 cells assessed as inhibition of calcium flux by FLIPR assay in presence of 30 mM of potassium				J Med Chem 55: 9847-55 (2012) Article DOI: 10.1021/jm301056k BindingDB Entry DOI: 10.7270/Q26W9C7J
					More data for this Ligand-Target Pair