BDBM50399760 CHEMBL2179427

SMILES: [#7]-[#6]-[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](-[#8])=O

InChI Key: InChIKey=YRFVDMSYFVWLJK-AQRCPPRCSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50399760   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50399760 (CHEMBL2179427) Show SMILES [#7]-[#6]-[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](-[#8])=O |r| Show InChI InChI=1S/C39H67N15O10/c40-16-6-4-12-24(32(58)51-25(13-5-7-17-41)34(60)53-27(37(63)64)15-9-19-48-39(45)46)50-33(59)26(14-8-18-47-38(43)44)52-36(62)29(21-31(56)57)54-35(61)28(49-30(55)22-42)20-23-10-2-1-3-11-23/h1-3,10-11,24-29H,4-9,12-22,40-42H2,(H,49,55)(H,50,59)(H,51,58)(H,52,62)(H,53,60)(H,54,61)(H,56,57)(H,63,64)(H4,43,44,47)(H4,45,46,48)/t24-,25-,26-,27-,28-,29-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	6.5	n/a
Universit£ de Sherbrooke Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant PACE4 expressed in Drosophila S2 cells using pyroGlu-Arg-Val-Lys-Arg-methyl-coumaryl-7-amide as substrate...				J Med Chem 55: 10501-11 (2012) Article DOI: 10.1021/jm3011178 BindingDB Entry DOI: 10.7270/Q2NV9KDZ
					More data for this Ligand-Target Pair
Homo sapiens furin (paired basic amino acid cleaving enzyme) (FURIN), mRNA (Homo sapiens (Human))	BDBM50399760 (CHEMBL2179427) Show SMILES [#7]-[#6]-[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](-[#8])=O |r| Show InChI InChI=1S/C39H67N15O10/c40-16-6-4-12-24(32(58)51-25(13-5-7-17-41)34(60)53-27(37(63)64)15-9-19-48-39(45)46)50-33(59)26(14-8-18-47-38(43)44)52-36(62)29(21-31(56)57)54-35(61)28(49-30(55)22-42)20-23-10-2-1-3-11-23/h1-3,10-11,24-29H,4-9,12-22,40-42H2,(H,49,55)(H,50,59)(H,51,58)(H,52,62)(H,53,60)(H,54,61)(H,56,57)(H,63,64)(H4,43,44,47)(H4,45,46,48)/t24-,25-,26-,27-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
Universit£ de Sherbrooke Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant furin expressed in Drosophila S2 cells using pyroGlu-Arg-Val-Lys-Arg-methyl-coumaryl-7-amide as substrate...				J Med Chem 55: 10501-11 (2012) Article DOI: 10.1021/jm3011178 BindingDB Entry DOI: 10.7270/Q2NV9KDZ
					More data for this Ligand-Target Pair